Talk:Phenazopyridine

Comment
Please note that I am by no means a pharmacist or chemist. I have only a moderate understanding of the chemisty involved in drug interactions. I started this article because I was put on this drug and immediately came here to look up information. My information comes mostly from the drug facts sheet contained in my prescription, and talks with my doctor. Kutulu 02:28, 19 Apr 2005 (UTC)

I suggest that the Criticism section be retitled, as the statements there are not, in fact, criticisms of the drug or its effectiveness/safety. Rather, they are opinions about how the drug might be used incorrectly. I can't suggest an appropriate new title, otherwise I'd make the change myself. Fshepinc (talk) 17:18, 18 October 2011 (UTC)

Precautions would be a more appropriate title than Criticism. Everything written under Criticism are legitimate and important concerns. (Mountaincedar (talk) 18:06, 12 February 2012 (UTC))

Exception to effectiveness as an analgesic for the urinary tract: the drug is widely used, but in cases of male cystoscopic procedures where the uretha wall is stretched beyond its elastic limits, leisions will occur; the drug is not effective at all in relieving severe burning pain in such cases. — Preceding unsigned comment added by 75.65.44.71 (talk) 14:42, 8 March 2012 (UTC)


 * Is there a citation somewhere that supports the claim that this drug is ineffective at relieving the pain of urethral lesions following cystoscopy? I just had a procedure last week with that result, and I'm on Phenazopyridine.  It definitely seems to be effective both for the kidney/ureter pain and the urethral lesion pain.  If I miss a dose and let my levels drop, my poor battered urethra hurts like crazy!  Anecdotally, it seems to work. 209.210.195.34 (talk) 05:12, 12 March 2012 (UTC)


 * Well, I have had a cystocopy which had to be aborted because of bleeding (my extremely enlarged prostate is "friable"). Neither Lidocaine Jelly nor phenazopyridine tablets seem to provide any relief from the intense burning whenever I piss into the Foley. I am very much interested in the citation.108.48.209.190 (talk) 18:36, 3 March 2013 (UTC)

Not an "official" site
A commercial link was removed from the website. http://www.phenazopyridine.com/about_us/ shows that this is a company (if the Google adwords on the side weren't also a cue-in) making money from their websites, not an official medical clearinghouse for the drug. This company also does not hold a specific patent on this drug, which is available over the counter and has no patent. Essentially, the "official" statement is BS. 98.196.202.92 15:29, 2 September 2007 (UTC)
 * Nice catch. It might be nice to point those who add such links to WP:EL and WP:SPAM. Fvasconcellos (t·c) 15:32, 2 September 2007 (UTC)

Utistat removed
I removed the entry "utistat(ciprofloxacin 250 mg+phenazopyridine 200 mg)" as it doesn't exist. There is a product called UTI-Stat but it is a cranberry-based product and contains neither ciprofloxacin nor phenazopyridine. Ænea ( talk ) 23:54, 16 June 2012 (UTC)
 * I also removed Urosina (phenazopyridine+nitrofurantoin) because the link supplied was broken and I cannot find any real verification for the drug's existence other than some Google entries that look to be Chinese. Ænea ( talk ) 00:08, 17 June 2012 (UTC)

Removed reference to phenazopyridine's efficacy when used during treatment of UTI's
Previously listed under "Medical Uses" section: "Phenazopyridine is not an antibiotic, but used in conjunction with an antibiotic can speed the early period of recovery from such an infection."

This was in error, from the Warner-Chilcott (manufacturer of Pyridium Plus) prescribing information file available at: http://www.wcrx.com/pdfs/pi/pi_pyridium_plus.pdf

"Treatment of a urinary tract infection with Pyridium Plus should not exceed 2 days because there is lack of evidence that the combined administration of phenazopyridine hydrochloride and an antibacterial provides greater benefit than administration of the antibacterial alone after 2 days."

The reference to phenazopyridine's usefulness when concomitantly administered with an anti-infective medication has been removed. I posted this section to inform readers who may have mistakenly thought that it improved the efficacy of antibacterial therapy. PA MD0351XXE (talk) 06:20, 4 July 2012 (UTC)

A urologist's perspective on Phenazopyridine
In 31 years of practicing (board certified) urology, I must say that Phenazopyridine is one medication among my "most often prescribed meds hit parade"; it is also my least favorite, in-fact, the most disliked in that repertoire. Patients all complain about "staining everything orange"; some complain about "foul odor", "sticky urine", "took two days to leave my system", and the list goes on from that perspective.

For some, the relief from urethral and bladder pain is adequate to good. For others, it provides little or no relief; I've even heard a few patients state that it made things worse (which I question).

"Phenazopyridine is not an antibiotic, but used in conjunction with an antibiotic can speed the early period of recovery from such an infection." I, personally, have not witnessed this to be a trait of the drug. I have, however, witnessed the OTC (97.5mg) version(s) available at most pharmacies mask the burning from a UTI for a period sufficient enough to allow the patients to become febrile; and a few times I've had to head into one of the ER's which I serve in the middle of the night for an on-call "urinary sepsis", a.k.a. borderline pyelonephritis (or sometimes, full-blown pyelonephritis).

Should you begin showing symptoms of a UTI, burning, clouding, odor, call and visit your health care practitioner, or if it's late in the day, call their answering service. They'll know how to best treat your symptoms and the underlying problem which caused it. Don't be afraid to seek emergency care for a urinary tract infection, as a UTI can become life threatening in the matter of a few short hours.

Until 2007, there was a prescription med called "Urised", which contained Methenamine, Hyoscyamine, Methylene Blue, and a few other "odds and ends". Urised was the preferred choice for prescribing by many urologists, but alas, the company which produced it had QC problems in their synthesis of methenamine, necessitating the drugs removal from the market.

Hyophen, a similar alternative to Urised, is not inexpensive. It is, however, a more attractive option for those who may have received a script for phenazopyridine who for some reason are apprehensive in taking it. It normally changes the color of your urine to a deep blue or blue-green color, and can be easily washed out of undergarments/clothing/linens.

Yes, it comes with it's own list of side effects, and a few drug interactions. Ask your prescriber and pharmacist about the med before considering its use.

Be sure to ask both your healthcare practitioner and your pharmacist about interactions between these medications and any OTC or herbal preparation which you are currently taking.

In essence, if Phenazopyridine works for you, then by all means, take it when necessary. If it doesn't, and you're in need of urinary tract analgesia, ask for the available alternative medication. PA MD0351XXE (talk) 04:26, 3 July 2012 (UTC)


 * Please work these concerns into the article itself, especially your first 3 paragraphs.108.48.209.190 (talk) 19:02, 3 March 2013 (UTC)

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source [2] is gone
Hi,

I just want to mention, that source [2] just leads to the start page of DailyMed. Couldn't find the corresponding entry.

https://www.ncbi.nlm.nih.gov/pubmed/12806392

http://ntp.niehs.nih.gov/ntp/roc/twelfth/profiles/phenazopyridinehydrochloride.pdf — Preceding unsigned comment added by 193.175.73.218 (talk) 14:49, 26 February 2019 (UTC)