Talk:Phenethylamine

Legal Status in NZ
Hi guys,

There seems to be some issues with the footnote for whether this compound is legal in NZ. Firstly, the reference isn't the correct way of referencing legislation or schedules within. Secondly, the reference may be out of date or incorrect as a search of that piece of legislation reveals no mention of it anywhere. Could someone please look into this? — Preceding unsigned comment added by ClubmanGT (talk • contribs) 22:11, 15 April 2016 (UTC)

Phenethylamine monographs
There is a LOT of content from these sources that needs to be added to the article.  Seppi  333  (Insert 2¢) 21:32, 20 September 2016 (UTC)


 * Hazardous Substances Data Bank:
 * PubChem:
 * Human Metabolome Database:
 * HMDB phenylacetic acid entry (PEA's primary metabolite from MAO-B+MAO-A-mediated oxidative deamination)

New review to add

 * - probably worth adding content from tables 3+4 and the article text.  Seppi  333  (Insert 2¢) 19:57, 30 January 2017 (UTC)

makes you feel like you're falling in love?
Could someone add something about the research about this chemical in chocolate and it allegedly causing a feeling of falling in love? — Preceding unsigned comment added by Skysong263 (talk • contribs) 23:36, 14 July 2019 (UTC)
 * Do you have some WP:RS in mind? Wikipedia is the encyclopedia anyone can edit, so feel free to write and cite. DMacks (talk) 02:10, 15 July 2019 (UTC)
 * chocolate doesn't have much to do with phenethylamine tbh, but phenethylamine itself is VERY wired in the brain pathways mainly in love and stuff like that. phenethylamine is released in massive amounts when your in love and is the main reason some often feel high off love. Doxylamine (talk) 04:19, 31 October 2023 (UTC)
 * I couldn't find anything supporting that PEA is released in situations where we would call "being in love" or other social situations except for physical sexual activity but there's other compounds from dopamine to epinephrine there. Eyes dilating from looking at someone sexually attractive has been attributed to Epinephrine. Some articles have claimed Oxytocin is one of the main reason people feel good from feeling in-love and there is some research supporting Oxytocin release in social situations outside of sexual physical activity. But it's likely not one single chemical. But either way couldn't find anything scientific in regards to PEA release to support the claim of it's relation to feeling in love. Gettinglit (talk) 22:16, 11 November 2023 (UTC)
 * i would say the 'love' feeling phenethylamine produces is much similar to what meth or coke does to people (making them horny or lovey) but a thousand fold at high doses and very very different despite similarity. I mainly feel phenethylamine in love when i first meet someone i really like (not as much once im used to them) and i get the exact same feeling phenethylamine gives me mixed with oxytocin and some other stuff. The love feeling is definitely a mix and not just pea but i would say its mainly phenethylamine, oxytocin, and serotonin. But I don't have any direct evidence except personal first-hand experiences but that doesn't count much for shit unless i have a study; but i'm very willing to bet pea is one of the main love hormones, like, 80-90% sure. 159.118.198.249 (talk) 20:12, 12 November 2023 (UTC)
 * Have a look at https://www.preprints.org/manuscript/202407.0336/v1 Ryochan (talk) 11:24, 12 July 2024 (UTC)

Is this a contradiction?
In the article's lede it states "in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by monoamine oxidase B (MAO-B)". However, further down in the "Detection in bodily fluids" section, it states "β-PEA would not be deaminated in the gut as it is a selective substrate for MAO-B, which is not found in the gut". These two statements are seemingly contradictory as the first one says it's metabolized in the small intestine (which is part of "the gut," is it not?) and the second one says it's not. Wondering if someone with more pharmacokinetics knowledge can clear this up. Lumberjane Lilly (talk) 14:07, 16 September 2021 (UTC)

Legal status in US
Phenethylamine is not scheduled but in United States v. McKinney (1996), the Court of Appeals for the Eighth Circuit ruled it to be an analogue of methamphetamine under the Federal Analogue Act. Shall we mention that in the article?

Source (page 40 of the PDF)

Amberkitten (talk) 22:59, 20 June 2024 (UTC)