Talk:Pramipexole

FALLING ASLEEP WHILE DRIVING?!!!!!
If anyone else has seen the commercial for this drug, the woman calmly recites that "Mirapex may cause you to fall asleep during normal activities, such as driving". Just how common is this? —Preceding unsigned comment added by Dogma5 (talk • contribs) 21:45, 5 December 2007 (UTC)

Response:

This is a very unusual side effect. Mainly all substances that mimic the effect of dopamine has adverse effects such as severe hypotension and sudden "sleep attacks". However, these side effects can be reversed. Medications that maybe allowed overcoming excessive daytime sleepiness are the class of selective Norepinephrine reuptake inhibitors. Since you are on a dopamine agonist, is it not recommended for you to take a "original" stimulant such as amphetamines, methylphenidate, caffeine, nicotine, etc. because those substances are known to increase dopamine and can worsen the side effects caused by the dopamine agonist.

Another possibility to overcome these symptoms is to talk to your doctor to see if you can gradually reduce the dosage instead of going "cold turkey" (that is; if your disease symptoms of Parkinson’s, restless legs syndrome or extrapyramidal symptoms are subsiding.)

Broken link
Link 12 doesn't appear to go to the article or page intended. (92.10.108.20 (talk) 19:59, 2 August 2009 (UTC))
 * I've replaced it with a reference to the actual study. Fvasconcellos (t·c) 20:13, 2 August 2009 (UTC)

Error in reference (1)
The second sentence states "[Pramipexole] is also sometimes used off-label ... to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.[1]" However reference [1] "Pramipexole Augmentation of a Selective Serotonin Reuptake Inhibitor in the Treatment of Depression" (J Clin Psychopharmacol. 20 (2): 274-275.) clearly states in its "Discussion" section that "Pramipexole did not seem to be effective in alleviating sexual side effects in this short trial." This is the only time the article mentions the efficacy of pramipexole on libido. Thus reference [1] serves to refute the usage of pramipexole to counteract problems with SSRI-induced sexual dysfunction, not support it. I was unsure as to whether the reference should be edited or deleted. Disconat (talk) 21:44, 3 September 2009 (UTC)

RLS/Parkinsons Off-label use, Compulsive gambling as a side-effect
Why are there no mention of these two things? --24.77.9.50 (talk) 22:01, 17 April 2013 (UTC)

I'm inquiring whether I can get pramipexole covered by pharmacare, I have restless leg so bad and nothing seems to help more than this medication. If I don't take this I'm up walking around half the night. It works so well, but I'm a senior on pension and it isn't covered and I really wish you could get this passed to British Columbia, Canada. Nothing works as well as your pramipexole. Can I please have this covered. I would really appreciate it. I'm on 0.25mg. My name is Edna Goertzen, my email address is          luckyleo_40@yahoo.ca. My address is        112-6601 tucelnuit Dr.  Oliver BC Thank you. ≠≠≠≠ — Preceding unsigned comment added by 76.11.60.58 (talk) 19:39, 14 November 2016 (UTC)

Duplication of side effects
Is it necessary to list the side effects in the opening, then list them again in their own section? I would argue this information is best presented in the side effects section only. Wlduggan (talk) 13:59, 15 June 2019 (UTC)