Talk:Pyridoxine

Heading

 * Thursday, February 12, 2009, FDA Declares Form of Vitamin B6 a Drug, Effectively Banning Pyridoxamine from Dietary Supplements www.naturalnews.com/025606.html
 * Friday, October 14, 2005, BioStratum spends millions on drug, finds central compound on Internet
 * On July 29, 2005, FDA received a citizen petition submitted, under 21 CFR 10.30, by the law firm Morgan Lewis & Bockius, LLP, on behalf of BioStratum, Inc. The petition requests that the agency: (1) State in writing that dietary supplements that contain pyridoxamine are adulterated under the Federal Food, Drug, and Cosmetic Act; (2) exercise its enforcement authority aragunder the act to remove from interstate commerce dietary supplements containing pyridoxamine; and (3) not place this citizen petition in the agency's docket for premarket notifications for new dietary ingredients (Docket No. 2004N-0454).

Function in the body, need for citations
I edited the first paragraph of this section and was somewhat dismayed at the date on the citation needed tag -- Feb 2007. Then I continued reading the article, and noticed the second paragraph also had a citation needed tag from the same date. Because the first tagged statement was decidedly contentious (claiming health benefits for a variety of conditions) I felt comfortable removing it, but the second paragraph is pretty much all solid information, and finding a citation for it should be as easy as opening a biochemistry textbook. Unfortunately, I don't have anything at hand, and I feel pretty strongly against internet citations, so that leaves me unable to do much. This article is decent but the lack of citations is a serious problem, and because it's on an important topic I feel it warrants the attention, which is why I'm writing here instead of just sighing and moving on to a different page as I usually would. Thanks in advance to anyone who addresses this issue. 70.132.140.16 (talk) 20:20, 2 February 2010 (UTC) cbnbb — Preceding unsigned comment added by 110.173.180.98 (talk) 06:42, 14 August 2012 (UTC)

Function in the body, Generalizing statements to make them factually accurate
This section should be reviewed further for accuracy. I'm changing it now to read: "B6 assists..." It previously read: "Pyridoxine assists... It is required for the production of the monoamine neurotransmitters...". This is factually false. Pyridoxine is not required for the formation of these neurotransmitters. The P5P form of B6 is required, which may be acquired from a normal dietary source pyridoxamine. Thus, Pyridoxine is not required to make these neurotranmitters at all. Someone is jumping to conclusions, or intentionally obscuring information. I doubt this section applies to pyridoxine specifically at all. Since pyridoxine is the common supplemental form of B6 found in multivitamins, it is marginally appropriate to include such things here... but it should be claims of what B6 does, not what pyridoxine does. Gd2shoe (talk) 19:22, 14 June 2013 (UTC)

Medicinal uses of pyridoxine
The penultimate paragraph of this section quotes a source as saying "21 % of women taking doses of less than 50 mg daily experienced neurological side effects". The reference quoted does not support this statement and I suggest it be regarded as factually incorrect. — Preceding unsigned comment added by 69.50.70.10 (talk) 18:00, 5 February 2012 (UTC)

Toxicity
Vitamin B6 is usually safe, at regular intakes up to 200 mg per day in adults.

This statement must be backed up or deleted! It's in direct contradiction to later, properly referenced statements such as "One study reported that over a 6-month period or longer, 21% of women taking doses greater than 50 mg daily experienced neurological toxicity." And the Wikipedia article on Vitamin B6 reports that regulatory bodies have established Safe Upper Limits (SULs) for this substance as low as 10mg/day. — Preceding unsigned comment added by 188.192.205.182 (talk) 10:42, 1 February 2014 (UTC)

Ugh - I just realized that the entire first half of that. section is copy-pasted from the web page of a Vitamin supplement salesman! That's not exactly a trustworthy source for information about safe upper limits. As an immediate measure, I'm removing any reference to specific dosages in excess of well-established SULs as being safe. — Preceding unsigned comment added by 188.192.205.182 (talk) 10:54, 1 February 2014 (UTC)

-- http://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/

Table 3: Tolerable Upper Intake Levels (ULs) for Vitamin B6. Adults: 100mg/day. ee1518 (talk) 15:35, 7 August 2014 (UTC)

WARNING ::::: PLEASE GET A CLEARER WARNING INTO THIS ARTICLE : I am presently apparently suffering the effects of Pyridoxine poisoning : I am heading toward physical helplessness -- Walking, balance, strength impaired ! ! ! . Most doctors are apparently unaware of this serious danger and so fail to consider this hazard ! ! ! — Preceding unsigned comment added by 2601:6C4:4000:DAEA:71AE:873E:1CA1:DD0C (talk) 06:45, 7 November 2018 (UTC)

To add to article
Basic information to add to this article: the etymology of the word "pyridoxine." 76.190.208.61 (talk) 20:23, 2 April 2021 (UTC)

Pyridine
Why is pyridine not mentioned even a single time in the current version of this article? 76.190.208.61 (talk) 20:27, 2 April 2021 (UTC)