Talk:Radiation-induced lung injury/Archive 1

Source list, to be worked in
Please feel free to add or cross off the list: Feel free to add or cross off - this is intended as a starting point to develop the article. MastCell Talk 18:55, 20 May 2009 (UTC)
 * General overviews:
 * Lung toxicity following chest irradiation in patients with lung cancer..
 * Radiation effects in the lung..
 * Injury to the lung from cancer therapy: clinical syndromes, measurable endpoints, and potential scoring systems..
 * Radiation and the lung: a reevaluation of the mechanisms mediating pulmonary injury..
 * Pathophysiology:
 * Link to our articles on biological effects of ionizing radiation in general
 * Role of oxygen free radicals and superoxide dismutase? Prevention of late effects of irradiation lung damage by manganese superoxide dismutase gene therapy. . Mouse study, >10 years old, ? anything more recent?
 * Cytokines: probably a whole separate topic, ? too much detail. Maybe focus on TGF-beta as the most studied cytokine in radiation injury:, mention prospective clinical trials incorporating TGF-beta: , ,.
 * Early vs. late effects (inflammation vs. fibrosis, need to find refs)
 * ? mention bilateral hypersensitivity phenomenon, or too obscure?.
 * Etiology/Risk factors:
 * Susceptibility: Distinct loci influence radiation-induced alveolitis from fibrosing alveolitis in the mouse..
 * Volume of lung irradiated, total dose of radiation, fractionation, concurrent chemo as risk factors (find refs).
 * Predictive models:,.
 * Signs/symptoms
 * Diagnosis
 * Treatment/prognosis
 * History?
 * Link in article to "pulmonary insufficiency" incorrectly redirects the reader to "pulmonary valve insufficiency." —Preceding unsigned comment added by 71.102.135.35 (talk) 21:17, 9 January 2011 (UTC)