Talk:Renin

Reference range
I added the reference several years ago under a different user name. I have updated it again. This is the reference range used by the hospital laboratory system in Hamilton Ontario, Canada.Andrew.e.gibson (talk) 20:16, 22 August 2009 (UTC)

Who is sure about renin concentration? mg/ml? A3camero: I'm a senior biomedical sciences student and going by my physiology notes, fairly sure it's mg/mL like everything else to do w/ blood levels. It could possibly be in ng/mL. A3camero (talk) 19:28, 9 April 2008 (UTC)

I have changed the normal adult reference range to the proper value. Gibby 15:29, 15 June 2007 (UTC)

Sodium/Na/NaCl?
There should be some uniformity with the use of "Na" vs. "sodium" Additionally, is it the plasma concentrations of NaCl which triggers renin or is it simply "Na" concentrations. —Preceding unsigned comment added by 75.177.3.51 (talk) 14:21, 22 September 2007 (UTC)

Confusing introduction
The introduction to this article is very confusing, and may be written in a little too technical a fashion. After reading it, I still have no idea what renin does. 12.75.46.82 (talk) 23:30, 9 December 2007 (UTC)

Merger
PRA is diagnostic test in its own right and deserves a separate article. If you can justify the merger, go ahead and merge....sarindam7 (talk) 12:34, 26 March 2008 (UTC)(created the page)

PRA is a medical test and has its own procedure. It's independent of the thing it's measuring just like ELISA is separate from the article on enzymes. Diagnostic tests and procedures often merit their own articles. A3camero (talk) 19:28, 9 April 2008 (UTC)

Remove the merger tag
Requesting any admin to remove the merger tag. Discussion isn't going anywhere. Separate articles wont harm.sarindam7 (talk) 11:01, 13 April 2008 (UTC)
 * Agree. Essay and protein are different things.Biophys (talk) 04:49, 27 January 2009 (UTC)

Orphaned references in Renin
I check pages listed in Category:Pages with incorrect ref formatting to try to fix reference errors. One of the things I do is look for content for orphaned references in wikilinked articles. I have found content for some of Renin's orphans, the problem is that I found more than one version. I can't determine which (if any) is correct for this article, so I am asking for a sentient editor to look it over and copy the correct ref content into this article.

Reference named "isbn1-4160-2328-3": From Follicle-stimulating hormone:  From Angiotensin:  From Calcitonin:  

I apologize if any of the above are effectively identical; I am just a simple computer program, so I can't determine whether minor differences are significant or not. AnomieBOT ⚡ 11:55, 2 September 2011 (UTC)

Research result -- will wait for additional results and reporting
http://www.sciencedaily.com/releases/2011/11/111109104208.htm

The study identified key genes, messenger RNAs and micro RNAs present in the kidneys that may contribute to human hypertension. It also uncovered two microRNAs that contribute to the regulation of renin -- a hormone long thought to play to part in controlling blood pressure. Although scientists have long known that the kidneys play a role in regulating blood pressure, this is the first time that key genes involved in the process have been identified through a large, comprehensive gene expression analysis of the human kidneys. It is also the first time that researchers have identified miRNAs that control the expression of the hormone renin.

Some more research identifying the mechanism as a baroreceptor
[https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.318711 Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis, Circulation Research (2021). DOI: 10.1161/CIRCRESAHA.120.318711] Phil (talk) 20:07, 4 August 2021 (UTC)

-- Jo3sampl (talk) 15:23, 10 November 2011 (UTC)

Hormone or enzyme?
In the introduction section it says that renin is an enzyme but further down in the biochemistry and physiology section it is stated that it's a peptide hormone. A quick Google search results in similar confusing statements. So is it an enzyme or a hormone or both - or do these categories somehow not apply to this substance? 85.179.64.86 (talk) 21:59, 23 December 2012 (UTC)

BothWawot1 (talk) 23:37, 23 December 2012 (UTC)

As I understand it, it is both as it acts as an enzyme on angiotensinogen and as a hormone at renin receptors. Someone with more technical knowledge than myself should include this in the article. Explanation in the introduction as to why it is not commonly referred to as a hormone (is it because of its enzymatic-hormonal duality?) would also be welcome. Anditres (talk) 11:36, 7 February 2022 (UTC)

"RAS" should be "RAAS"?
This article says that "The RAS also acts on the CNS to increase water intake..." without defining RAS. Should this be "RAAS" instead of "RAS"? — Preceding unsigned comment added by 69.196.131.196 (talk) 19:05, 28 May 2015 (UTC)