Talk:SRT-1720

SRT1720 claim as an activator of SIRT1 has been refuted
Please see Pfizer's well recieved peer reviewed journal article refuting Sirtris' claims. In a nutshell, 1. Apparent activation of the enzyme is shown clearly to be a "non-natural substrate specific" artifact of the assay system. 2. Animal study results could not be reproduced with severe adverse effects of the compounds noted at high doses.

Tom McDonagh

74.9.55.102 (talk) 02:20, 13 January 2010 (UTC)