Talk:Selective serotonin reuptake enhancer

First hand experiences?
I've been struggling with depression for several years now. Most SSRIs and SRNIs on the market have been tried, with varying success and side effects (excess sweating and decreased libido are the most common for me). I'm really tired of the "here's a new drug, lets try it"-rigmarole. But none of the psychiatrists have considered SSREs as an alternative. Is there a reason for this? Do SSREs only work in specific cases? The article really is a stub.

Aldon954: I've tried every SSRI in existence. Only the tricylic antidepressants work for me. But, I have terrible ADHD so I can't mix my ADHD medicine, Vyvanse, with a tricyclic antidepressant due to cardiovascular contraindications. Every single SSRI I have tried has set me into a downward spiral of mild serotonin syndrome and increased depression, anxiety, and everything else it's supposed to fix! I am very motivated to try a medicine which works in the exact opposite way (either by mechanism of action OR indirectly). If it works, it would explain a lot about why it's not approved in America... or is it? Correct me if I'm wrong, by three pharmacists told me it's not available or approved in the United States.

Other SSREs
"The only known drug of this class is Tianeptine..." - not true, there is also the drug Amineptine which is also a selective serotonine reuptake enhancer, although it was never approved by the FDA and its market approval for France was revoked in 1999 due to heavy side effects (source: Wikipedia). Should drugs without market approval be mentioned in this context? — Preceding unsigned comment added by 77.23.170.114 (talk) 15:13, 30 September 2012 (UTC)
 * Amineptine is a dopamine reuptake inhibitor. — Preceding unsigned comment added by 86.101.2.3 (talk) 16:57, 25 November 2012 (UTC)