Talk:Sevoflurane

"Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology" Is this comment verifiably true? Would someone "in the know" say that sevoflurane is the most commonly used volatile anesthetic in adults? Thanks... Mlbish (talk) 19:29, 3 April 2008 (UTC)

Replacing Iso?
I think the comment re. Sevoflurane replacing Isofluorane is overstating the case a little. Certainly in UK practice, Isoflurane is still by far the most commonly used agent in adult anaesthesia. It works well and is significantly cheaper than Sevoflurane (not to mention vastly less than Des). In the current economic climate pressures are increasing to justify any increased cost in an anaesthetic so I can't see the status quo changing in the foreseeable future. Other than that, good article. Thunderbirdchris (talk) 09:58, 15 January 2011 (UTC)

It is replacing other agents to a significant extent in the UK, cannot say in other jurisdictions. Some units are favouring isoflurane on cost grounds.

It may be better to say "Together with desflurane, it is replacing isoflurane and halothane in many hospitals in the first world. Other hospitals have elected to continue to use older agents, especially isoflurane which is considerably less expensive though has more prolonged recovery times. It is administered in a mixture of nitrous oxide and oxygen or commonly nowadays at in oxygen enriched air though this needs a higher concentration of sevoflurane.

Skinner doc (talk) 12:53, 7 June 2011 (UTC)

Contradiction?
This article, citing two different sources, says &#8220;Sevoflurane has lower values of controversial bispectral index than desflurane,&#8221; but the article on desflurane, citing one of the sources, &#8220;A recent clinical study found that desflurane has lower bispectral index and greater hypnotic effect than sevoflurane during the equipotent anesthesia.&#8221; The source cited by both articles says, &#8220;[O]ur findings suggest a distinction between the analgesic and hypnotic effects of volatile anaesthetics, such that volatile anaesthetics have different ratios of hypnotic to analgesic potency.&#8221;  The other source, cited by only this article, is too technical for lay readers to understand. Bwrs (talk) 01:24, 10 July 2015 (UTC)

18May2021 - Kudos to whomever updates this page! 50.39.177.30 (talk) 19:50, 18 May 2021 (UTC)

PANDA/GAS trials
It seems like the PANDA and GAS clinical trials have concluded, making this article's info on them out of date. Guyy8fh (talk) 22:19, 25 September 2021 (UTC)