Talk:Somatic cell nuclear transfer

Wiki Education Foundation-supported course assignment
This article was the subject of a Wiki Education Foundation-supported course assignment, between 11 January 2021 and 21 April 2021. Further details are available on the course page. Student editor(s): ConnerButcher16.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 09:47, 17 January 2022 (UTC)

Updates to SCNT epigenetic memory
False claim when talking about the rigidity of iPSC cells epigenetic memory. Updated it to include a discussion of techniques used to reset iPSC epigenetic memory.

Introduced challenges stemming from the epigenetic memory of SCNT as a possible reason for low yields in cloning. Included primary paper as supporting evidence.

Included links to stem cell controversy page. Once in the 2nd paragraph "Therapeutic cloning refers..." and in the second paragraph of stem cell research subheading "Embryonic stem cells...". Also linked embryonic stem cells in the same paragraph to the embryonic stem cell page. — Preceding unsigned comment added by Dkennedy12 (talk • contribs) 00:31, 16 December 2021 (UTC)

somatic cell
Are there organelles besides mitochondria that have DNA/RNA? I'm pretty sure there aren't. 68.6.190.89 04:55, 19 April 2006 (UTC)
 * Only in plants, where chloroplasts have DNA as well. It's just mitochondria in animals. TimVickers 21:39, 21 October 2006 (UTC)

merge with Therapeutic cloning
I am merging this page with the one on therapeutic cloning. 'Therapeutic cloning' is simply a (misnamed) application of the SCNT process. - User:Jesse Reynolds 23:05, 25 September 2006 (UTC)
 * I disagree. I have been reading through articles on therapeutic cloning, ie. SCNT with the subsequent cells used to derive specific semi/fully-differentiated cell types of clinical value, and find no such useful information on the SCNT page. Especially with all the ridiculous hoopla amongst lay people concerning cloning technology it would probably also be good to have separate entries f4 pages might be more organized? Thanks! --Xris0 (talk) 06:04, 7 January 2008 (UTC)

Expansion
I elaborated the sections on SCNT in stem cell research, controversy, and policy. These were made fairly consistent with the page stem cell controversy. A number of paragraphs were edited, and a few sentences removed, due to inaccuracies. I need to add some footnotes, and plan to do so soon. --Jesse Reynolds 01:24, 6 October 2006 (UTC) yet i still want to know in depth what therapeutic cloning is and i want to know why and when therapeutic cloning was first introduced. also how is therapeutic cloning different from other types of cloning.

Citation
I added and improved several references to this article, could editors try to use high-quality peer-reviewed sources in this article, as it deals with a scientific area. Thank you. TimVickers 21:39, 21 October 2006 (UTC)

Vandalism
I corrected some vandalism in the "process" section, but my text may be inaccurate. Could someone follow up for me? Mike — Preceding unsigned comment added by 128.205.230.143 (talk) time, 03:18, 9 November 2006 (UTC)

External link
FAO: Tim Vickers, I agree in principle with your comment posted on the SCNT page. I would however suggest that A) The aforementioned article deals with both reproductive and therapeutic cloning, B) There is no reproductive cloning page on Wikipedia and C) Somatic cell nuclear transfer (SCNT) *is* both reproductive and therapeutic cloning as this is the core procedure in both cases, thus I believe it is pertinent to include a discussion of these forms of cloning from a personal perspective, so I have re-included the webpage link. Kind regards, George

Hi George. The article briefly touches on therapeutic cloning and doesn't mention the technology of SCNT at all. Instead it is a discussion of the ethics of reproductive cloning. Reproductive cloning is dealt with in the Human cloning article. I have moved your link to this page. TimVickers 01:07, 18 November 2006 (UTC)

Suitable somatic cells
This article should mention explicitly that epigenetic modification precludes nuclear transfer from producing viable embryos from many somatic cells (preferrably with some examples). It needs more than lip service to reprogramming, particularly since the epigenetics article is so much better than the reprogramming one. Psyno 15:46, 11 April 2007 (UTC)

Title of this article
The therapeutic cloning has been merged into this article. So in my opinion the title may be changed to "Cloning Technique" or something else.--!Panzerkampfwagen! (talk) 08:11, 1 February 2018 (UTC)

Wiki Education assignment: Developmental and Molecular Biology Spring 2024
— Assignment last updated by Bfleeger2020 (talk) 18:54, 13 April 2024 (UTC)

Added "Early 2oth-Century" section
Hi all. I just wanted to say that I have added a section detailing the research of Sir John Gurdon and his work on SCNT in the 1950's. JillPill09 (talk) 04:10, 8 April 2024 (UTC)