Talk:Stroma (tissue)

Untitled
Stroma, as a tissue, must be viewed in a broader sense than now, which is strangely limitated to animal tissue. In histology stroma is used to refer to any surrounding and suporting connective tissue in an organ, not only in animals, so also in vegetal structures o mycological preparations. --Bestiasonica (talk) 23:31, 17 November 2012 (UTC)


 * In order to assess my opinion is that this article must be rated at Stub / mid level. --Bestiasonica (talk) 23:35, 17 November 2012 (UTC)

Inaccurate content
MCB importance should be high; I am surprised at the lack and accuracy of content here.The fundamental definition of stroma given here as having a structural role and not contributing to the function of an organ is extremely out of date, and entirely incorrect. For example, lymph node stroma has an important role in antigen presentation within the B cell follicular regions, and stromal remodelling following vaccination or infection is highly important for effective immune function. Stromal cell biology is a large field, from organogenesis/embryology to stem cell/regenerative medicine and stromal cell immunology. This article would be better if reduced to its first sentence, no facetiousness intended. 143.167.166.41 (talk) 01:08, 2 March 2016 (UTC)

Need explanation of tumor stroma
Cancer related articles mention stroma but don't explain it. Should it be a section in this article ? or in tumor/neoplasm ? Could use The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer. for detail ? eg it says "The tumor stroma basically consists of (1) the nonmalignant cells of the tumor such as carcinoma-associated fibroblasts (CAFs), specialized mesenchymal cell types distinctive to each tissue environment, innate and adaptive immune cells,13, 18 and vasculature with endothelial cells and pericytes19, 20 and (2) the extracellular matrix (ECM) consisting of structural proteins (collagen and elastin), specialized proteins (fibrilin, fibronectin, and elastin), and proteoglycans (Table 1).21" and "During early stages of tumor development and invasion, the basement membrane is degraded, and the activated stroma, containing fibroblasts, inflammatory infiltrates, and newly formed capillaries, comes into direct contact with the tumor cells" We could confirm that the stroma is a component of the tumour, rather than a layer around a tumor ? - Rod57 (talk) 12:25, 2 May 2016 (UTC)