Talk:Tizanidine

Package Insert
this article reads much too much like a package insert, from which i suspect much of it is copied. phrases like 'care should be taken' etc., it seems tome, constitute medical advice, which wp seeks to avoid.Toyokuni3 (talk) 16:07, 1 March 2011 (UTC)


 * I definitely agree that the writing is not up to the Wikipedia standard, and the language used makes it seem copied from another site, if not necessarily from the package insert. Remember, we do not reproduce copyrighted material.


 * I can tell you today, if it isn't widely known yet, that this drug is showing up on the black market, as a would-be Xanax. So all the facts are needed. The article on Quetiapine (Seroquel) is an excellent example! I wouldn't have believed anybody, even in prison, takes an antipsychotic recreationally, if I hadn't read it there.


 * --Ben Culture (talk) 02:31, 24 January 2013 (UTC)

Availability
Unfortunately I don't have anything to contribute, but this is quite possibly one of the most poorly written sections I've ever read on Wikipedia. It could at least be turned into a list, rather than the mammoth barely-readable paragraph it is right now. — Preceding unsigned comment added by 101.171.190.188 (talk) 12:49, 13 November 2011 (UTC)
 * Agreed... seriously, the pill descriptions are overkill and incredibly clumsy. --Cabazap (talk) 05:29, 19 December 2011 (UTC)

Many years ago, I worked with drug monographs on a daily basis, and Availability meant availability in the body, i.e, how fast the drug is dissolved, goes into the bloodstream and from where, does its job, how fast it re-enters the bloodstream if it does. This varies widely from drug to drug and with different methods of administration. Below Availability, there's a small section with a stab at this, but it's incomplete. Not being a pharmacologist or chemist, I will not attempt to dig through references and put this sort of information together, but someone with training needs to. As far as the description of pills on the market, pills change with each drug company merger or move to a new manufacturing facility. If the listing of pills and their descriptions stays in, it should be in a list, but I agree it doesn't need to be there. A brief listing of the available dosage strengths in pills would be appropriate. I will say that the writer who put together the paragraph on pills did a lot of time-consuming research. --derry (talk) 03:51, 20 January 2012 (UTC)

Pill Descriptions??
Why are the pill descriptions in there at all? there was talk about them earlier but they're still there. There are hundreds of different pill types out there. Should descriptions be listed for all available formulations for all pharms???? — Preceding unsigned comment added by 216.105.208.2 (talk) 07:37, 16 August 2012 (UTC)

Interactions
removing the Kg from the L/Kg for volume of distribution. I recall from pharmacology (and confirmed by going to the Wikipedia page :-) http://en.wikipedia.org/wiki/Volume_of_distribution ) Volumes of distribution are given only in units of L, there isn't a mass component to the unit. Mini  apolis  02:09, 11 December 2018 (UTC) — Preceding unsigned comment added by MikenStL (talk • contribs) 08:43, 12 July 2013 (UTC)

Abuse potential
The article currently says, in the Side Effects section: "Tizanidine has drug abuse potential. It has been recognized to cause dependence and addiction."

But this is not supported by the source. The source says nothing of dependence or addiction. It also doesn't say anything of abuse potential: it simply says that of the (fatal) poisonings in their database, of those that involved a pharmaceutical without a prescription, that tizanidine was implicated in some number of those. It does not distinguish poly-drug combinations, especially with illegal drugs, nor cases of intentional drug overdose. Number of deaths where the person had tizanidine in their system does not equate to abuse potential.

There is physical dependence, analogous to how clonidine has physical dependence, but this is not related to addiction potential / psychological dependence potential.

I am going to remove the above quoted text. If someone wants to re-add it, please use a source supporting the claim directly.

Kimen8 (talk) 22:37, 27 January 2024 (UTC)