Talk:Tolperisone

comparativ study with thiocolcicoside
if any comparative study availabe please inform. —Preceding unsigned comment added by 115.117.157.182 (talk) 17:59, 3 February 2010 (UTC)

more information about tolperisone
http://www.japi.org/february_2010/Article_17.pdf ... half-life of tolperisone is 1,5 - 2,5 hours. — Preceding unsigned comment added by 178.235.75.252 (talk) 10:45, 4 August 2013 (UTC)

Interactions grossly understated
From the patient information leaflet (last revised: February/March 2013) of the Cypriot distributor (M. K. Stavrinos), section “warnings and precautions:”

Hypersensitivity reactions range from mild skin reactions to severe systemic reactions (e.g. allergic shock). The following groups have a higher risk of experiencing hypersensitivity reactions: women, patients of older age, and patients treated with other medication concurrently (mainly with NSAIDs ), patients with drug allergy or allergic diseases or conditions (such as atopy: hay fever, asthma, atopic dermatitis with high serum IgE, urticaria) in the past history, and finally patients who suffer from viral infections during the course of the tolperisone treatment. Early signs of hypersensitivity include flushing, rush, severe itching of the skin, wheezing, difficulty breathing (with or without swelling of the face, lips, tongue, and/or throat), difficulty in swallowing, fast heartbeat, low blood pressure, fast decrease in blood pressure.

Note: This is not a direct quote from the leaflet. I can upload an image of the leaflet upon request.

Can someone with the necessary knowledge edit the interactions section please?

62.195.45.181 (talk) 17:35, 4 March 2016 (UTC)