Talk:Toxic epidermal necrolysis

The first line implies it is freqently induced by medication. Perhaps it should be reworded. —Preceding unsigned comment added by 188.220.95.192 (talk) 22:02, 22 October 2009 (UTC)

Apoptosis or necrosis?
The article says: "Keratinocytes, which are the cells found lower in the epidermis, specialize in holding the skin cells together, undergo necrosis (uncontrolled cell death)."

The emedicine article I cited says: "Current opinion suggests that epidermolysis is the result of keratinocyte cell apoptosis"

I hesitate to change it because of the name of the condition - necrolysis? Plus, I know nothing about it. Is there controversy? Or do both occur to an extent? If someone could clear this up, it would be great. Thanks, delldot   talk  06:20, 13 December 2007 (UTC)

A recent copyvio
The latest sweeping change in closely resembles an article I found online,

http://emedicine.medscape.com/article/229698-overview

Please revert to avoid WP:COPYVIO and add a short summary and a link to the article in the appropriate section.--ilgiz (talk) 17:36, 13 April 2009 (UTC)

Reviews
Three authors, two huge reviews in JAAD: part 1 and part 2. In case someone has a few hours to update this article. JFW &#124; T@lk  09:48, 11 September 2013 (UTC)

Working on updating this page with information from the aforementioned JAAD review articles. Jmtseng (talk) 21:59, 28 October 2014 (UTC)

Peer feedback
Hey Jmteseng, great work so far on this article. I noticed you've focused most of your edits in the lead, as well as adding important citations and links, and adding information to the pathogenesis and pathology sections. Feedback on these portions: The lead is a great introduction to the article, giving clear, easy to understand pieces of information to frame the rest of the article. The citations you added are great, reliable articles and really add to the quality of the information. Something I found myself wondering about while reading the article was the timing of the disease (how long it takes to develop symptoms after exposure to the offending agent, how long it can take to recover, etc.) Have you though about adding this information? Also perhaps more pictures, specifically of necrosis, and of Nikolsky's sign, may round out the article a bit more. Finally, I feel that the signs and symptoms section, since it is something that will be read by many, perhaps could be worded a little less technically. Have you though about updating this section with more easy to understand language? Keep up the great work, this article is super informative and a great resource to medical and non-medical people! DrPFili (talk)


 * Thank you for your feedback! Time from drug exposure to presentation is a great piece of information to add. Alas, I've tried to add more pictures, but unfortunately, there are limited pics in the wikimedia database and many restrictions on using pics from the web due to copyright issues. Good advice on the technicality bit. Walking the line between providing accurate but readable information was a challenge. I will work on making the s/s section more reader friendly.

68.65.175.22 (talk) 23:09, 17 November 2014 (UTC)

I have just recovered from this and so have added a couple of pictures, early stage and at peak. pics are of me so no copywrite :-) Jay2Base (talk) 11:10, 20 March 2018 (UTC)

Formatting Question
Any wikipedia preference in listing causal drugs/meds in paragraph vs bullet form? Jmtseng (talk) 02:59, 19 November 2014 (UTC)

Food concomitance?
The list of medications points suspiciously to diseases, conditions and antagonisms an issue Africans would settle with traditional cannibally or changing skin coloration. — Preceding unsigned comment added by 98.113.167.2 (talk) 14:47, 8 May 2016 (UTC)

Who is the Lyell in "Lyell's syndrome"?
Equinox ◑ 13:13, 27 August 2017 (UTC)