Talk:Trp operon

Context
Could you please provide a general description of what this article is talking about before going into the specifics? What part of Molecular Biology is it to do with and why is is important etc. Thank you. Mehmet Karatay 21:23, 24 June 2007 (UTC)

Repression section is not complete
The product of the Trp operon can be repressed in two ways: 1) the method mentioned in the article is termed "long term control" and is regulation at the transcriptional level. 2) there is a "short term control" regulation which regulates at the enzymatic level post-translationally via high levels of tryptophan alosterically inhibiting anthranilate synthase. Since anthranilate synthase is inhibited, the end product of L-tryptophan cannot be made. --98.70.130.148 (talk) 02:05, 26 February 2010 (UTC)

Attenuation and the mechanics of 1-2 hairpin
I have no sources to quote for this, but I've seen the point made, that since transcription and translation isn't separated in prokaryotes, the immediate and ongoing translation of the RNA will make the ribosome occupy sequence 1, blocking the potential hybridization of 1 and 2, leaving a hybridized formation redundant and improbable. Since this isn't specifically referenced, it would be nice to have some sort of clarification, if indeed someone is qualified to do so with authority. —Preceding unsigned comment added by Madskile (talk • contribs) 15:22, 10 May 2011 (UTC)

trp operon
The title is supposed to be trp operon, not Trp operon, according to the proper naming convention. I'm not sure how to change it, so I hope someone else can get to it soon!

Edit: Well I've formatted the displayed title. Hope that'll suffice.

Iyentra Rasonica (talk) 03:40, 31 October 2013 (UTC)

Discovery
Is there any relevant source about the year of the discovery? Year 1953 is earlier than the discovery of lac operon and even the first use of term operon (1960) — Preceding unsigned comment added by 158.42.76.243 (talk) 11:09, 17 April 2014 (UTC)

Promoter and R?
"It also contains a promoter where RNA polymerase binds to a repressor gene (trp R) which synthesizes a specific protein." This reads as if the trp R gene is located inside the promoter. Surely that's not the case? Bdellovibrio (talk) 09:19, 9 May 2014 (UTC)

Assessment comment
Substituted at 09:19, 30 April 2016 (UTC)

Wiki Education assignment: CHEM 378 - Biochemistry Lab - spring 2023
— Assignment last updated by Euqord (talk) 22:42, 15 May 2023 (UTC)

Persuasive Language, Redundancy, Lack of WikiLinks and Lack of Definitions for Abbreviations
There are instances of persuasive language such as "the fact that," and "this attentuation mechanism is experimentally supported." It is up to the discretion of the reader to determine whether something is a fact or if it is supported experimentally.

The possible secondary structures are discussed in two separate paragraphs.

Terms such as mutational analysis and structural modulation may not be known by the viewer, so an attached link would be helpful.

"nts" is an abbreviation that was not previously defined but is used in the sentence "the ribosome is proposed to only block about 10 nts downstream"

Euqord (talk) 22:02, 15 May 2023 (UTC)

Wiki Education assignment: CHEM 378
— Assignment last updated by Lakemicriver (talk) 18:46, 4 May 2024 (UTC)