Talk:Vardenafil

Chemical structure
Is the chemical structure for Vardenafil wrong ? It's the same as for Viagra, and looks like a Viagra molecule found on chemfinder.com. I couldn't find a Vardenafil chemical structure thought.

27 Apr 2005


 * The structures of sildenafil and vardenafil are similar, but this is indeed the correct structure of vardenafil. You probably don't have access to MIMS, but RxList has a monograph with the structure. Techelf 10:06, 28 Apr 2005 (UTC)

Priapism
I just had to put that bit in about what to do in the event someone takes this drug and winds up getting a hard-on that lasts for more than four hours.


 * JesseG 02:44, 10 Jun 2004 (UTC)

Contains pieces of the viagra page
The levitra page (this articvle) contains pieces of the viagra article, liek the home page, and "cialis and viagra are competitors to viagra" which I just fixed, there is more viagra "copy-paste stuff" on here that has to be changed to refer to levitra. I dont have time to fix it or identify every problem, srry, but I know they exist.Patcat88 04:06, 11 Feb 2005 (UTC)
 * I added the three link line because there are three products, well, actually four, I forgot about the other one, so I started to link the products. Because I was working on the three articles at once I may have forgotten to change the wording you mentioned. Sorry about that. There also seems to be a connection from a media blitz standpoint with the notorious Dr. Brinkley of the 1930s who also cashed in on male impotence . While this may be a genuine medical problem I find it difficult to believe that these 4 products which so dominate television advertising that they give the impression that the USA is in crisis mode with a flu like virus sweeping across the nation. I think that all of these products need grouping into one and then linked to a sensible article about the subject itself. By the way, I got to that subject by working on Mexican border blaster radio station articles and one about Dr. Brinkley. I will see what I can do to link these drugs to one central subject matter. MPLX/MH 04:51, 11 Feb 2005 (UTC)
 * I was trying to think of the name of this other annoying commercial and I remembered that its name is Enzyte and according to the CBS News web site this thing is a "nutritional product" not FDA approved and made by Berkeley Nutritionals who the Center for Science in the Public Interest (CSPI) has filed a complaint against with the Federal Trade Commission (FTC). The company is also under scrutiny by the Ohio State Attorney General’s office and the target of two class-action lawsuits looking for customer refunds. What bugs me most is that this scam was promoted heavily over Court TV! MPLX/MH 05:04, 11 Feb 2005 (UTC)
 * Since this was a stub I am merging all 4 stubs with the main article on Impotence in the hope that we can create one good article there instead of 4 stubs and a partial article


 * If I may suggest an alternative - you may like to create one good article on PDE5 inhibitors in general since there is a lot of common information, and have short articles on any specific information about each drug (sildenafil, vardenafil, tadalafil). This is quite a logical format for presenting drug information, and is similar to what is used in the Australian Medicines Handbook and the British National Formulary. See H2-receptor antagonist (cimetidine, ranitidine, etc) for an example of what I mean. Techelf 10:06, 13 Feb 2005 (UTC)

Hypotension?
Should the link to hypertension be hypotension? DaveCs 13 March 2006
 * Hypertension is correct. Vardenafil is infrequently associated with hypertension, and only rarely with hypotension. -Techelf 07:57, 14 March 2006 (UTC)

worth mentioning one study for pulmonary hypertension?
Hello, I did some checking, and apparently there was one study comparing this drug with sildenafil and tadalafil, which found that vardenafil did not cause "a significant reduction in the pulmonary to systemic vascular resistance ratio." This was something I found on the web, I forget the address, but it's called US Respiratory Disease 2006", authors Manu Jain and Anna P. Lam. I'm sorry I don't have any more details. Would it be worth mentioning this in the article, or should it be skipped until/unless a larger scale study is done? Thanks. -- Kyok o''  19:24, 10 April 2007 (UTC)
 * I've found the link. I'll have a read later, but IMHO this should be brought to WP:CLINMED for some extra opinions. Fvasconcellos 19:32, 10 April 2007 (UTC)

Viagra Relevance
"In 2000, Viagra sales acccounted for 92 per cent of the global market for prescribed Erectile Dysfunction pills.(pdf)"

How relevant is this? It seems in 2000 the ED market was in a very immature stage, I think it's time for an update or a removal of this "Market" section. Megacake (talk) 06:40, 8 June 2008 (UTC)

Patent issues and expirations
Someone should add info. re. patent issues and expirations like the Viagra Wiki entry


 * Looks like they expire sometime in 2018.
 * https://www.drugpatentwatch.com/p/tradename/index.php?query=LEVITRA
 * Phantom in ca (talk) 13:00, 7 October 2018 (UTC)

According to your link, they expire some time in 2023. Kiltpin (talk) 18:45, 17 November 2019 (UTC)