Talk:X chromosome

Interesting
Interesting things about the x chromosome: --nixie 00:17, 14 Feb 2005 (UTC)
 * X-linked disorders, dosage compensation, genes on X associated with genetic disorders
 * X-inactivation in human females and the gene XIST, Barr body
 * X chromosome sequencing

Nice article. Dhiraj Haloi (talk) 01:36, 23 November 2020 (UTC)

Expansion
Added information about the structure and sequence of X from a 2005 nature article --Smelissali 03:23, 21 October 2006 (UTC)

I added the expansion template tag to the article. I think it needs more information about the genes in the chromosome, about its function in other animals, etc... The article about the Y chromosome, which is smaller than this, has more content --Mindeye 08:14, 7 July 2006 (UTC)

Variance in IQ between the sexes and the role of the X chromosome
Is there somebody knowledgeable about the following? Different sources (e.g. Prof. Hameister in Ulm) state that a larger part of the inherited intelligence is carried by genes on the X chromosome and add that this was the reason for different variances in IQ between the sexes - there are more men who have very high and very low IQs compared to women. Christian Storm 16:48, 28 February 2007 (UTC)

I think you will find that the differences are in the spread of the distribution curves with the female curve having more area closer to the average IQ. This makes sense from an evolutionary point of view as males are disposable (A single successful male human can father hundreds of children, but a female can produce an order of magnitude fewer.) therefore a species can take risks with their DNA configuration whereas females, due to their different reproductive role, need to be more consistently capable. i.e. X-linked mental retardation is the price we pay for males also being capable of genius. This is not intended to sound sexist, or to imply that females cannot have a genius level IQ, it just suggests that the ones that do are more exceptional than their male genius peers.

On a related note, if we can have X-linked disorders than it does stand to reason that we also have X-linked extraordinary abilities, but what are they? I guess an examination of the roles of the specific genes on the X chromosome will indicate what areas these (theoretical) positive mutations can influence. — Preceding unsigned comment added by 124.187.99.149 (talk) 23:27, 1 May 2015 (UTC)

Dead Ref. links in this part of Article
Triple X syndrome (also called 47,XXX or trisomy X):

This syndrome results from an extra copy of the X chromosome in each of a female's cells. Females with trisomy X have three X chromosomes, for a total of 47 chromosomes per cell. The average IQ of females with this syndrome is 90, while the average IQ of their normal siblings is 100 [1]. Their stature on average is taller than normal females. They are fertile and their children do not inherit the condition. [2]
 * This part of the article has to be looked at, as there are no Ref's now that the outsite Links are dead. — Preceding unsigned comment added by 86.135.140.111 (talk) 23:32, 15 July 2011 (UTC)

Any system as to which genes go there?
Is there any tendency or systematic about the kinds of genes that tend to end up on X (rather than one of the autosomes) in mammals? Please add. -- 92.231.117.237 (talk) 17:48, 29 July 2012 (UTC)

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Genes listed on this page
I was curious about how the genes listed on this page were chosen and what the purpose of the list is. Given that zygotes without an X chromosome are nonviable and X-linked disorders are common, I would have expected to see a list that highlights some genes that are essential for life and help explain why the X chromosome is essential, or some genes that have known relevance to X-linked disease. The list instead appears to be comprised chiefly of genes that are not well-characterized. I'm not trying to argue that the genes listed are not important, but given the state of things now I would argue that the list is not particularly helpful to someone trying to learn about the X chromosome. 18.111.124.163 (talk) 16:57, 23 October 2017 (UTC)