Template:Did you know nominations/John Hughes (neuroscientist)


 * The following is an archived discussion of the DYK nomination of the article below. Please do not modify this page. Subsequent comments should be made on the appropriate discussion page (such as |this nomination's talk page, the article's talk page or Wikipedia talk:Did you know), unless there is consensus to re-open the discussion at this page. No further edits should be made to this page.

The result was: promoted by Yoninah (talk) 21:57, 21 January 2017 (UTC)

John Hughes (neuroscientist)

 * ... that neuroscientist John Hughes shared the 1978 Lasker Award for co-discovering opioid peptides in the brain? Source:
 * ALT1:... that neuroscientist John Hughes shared the 1978 Lasker Award for co-discovering enkephalins? Source:
 * ALT2:... that neuroscientist John Hughes isolated enkephalins after trading whiskey for pig brains? Source:
 * Reviewed: Komboni

Created by Tryptofish (talk). Self-nominated at 00:55, 11 January 2017 (UTC).


 * Symbol question.svg Nominated for DYK two days after creation, and is just over 1900 bytes, satisfying length and date criteria. QPQ is in progress. The phrase "where he would trade bottles of whiskey to the butchers in exchange for pig brains" isn't quite correct; he exchanged the bottles for pig heads, from which he extracted the brains (I guess this may be somewhat pedantic). However, he dug the pig brains out at the slaughterhouse (per source 6), and used the acetone to create "soup", not extract the brain. The article is well-sourced, though I would prefer page numbers in the citations where possible (eg -from source 5). I'll accept reference 1 despite being published by an organization with affiliation to the subject, as it is supplemented with other references which support some of its claims. As I didn't find the terms "met-enkephalin" and "leu-enkephalin" in the sources, can you explain this. I assume (from this) that Hughes discovered two peptides referred to as enkephalins, and that met- and leu-enkephalin are the only two enkephalins, ergo, he discovered these two peptides. (I base this on the three enkephalin articles.) Is my interpretation correct? Hooks are OK, and "brains" is acceptable for ALT2 irrespective of my concern about head/brain above, as the intention is clear. Anyway, only a few minor issues to address. Mind  matrix  14:50, 15 January 2017 (UTC)
 * thank you very much for the thoughtful feedback.
 * Pig "heads" versus "brains": I made this edit:, to clarify that point.
 * Acetone "extraction": I realized from your comment that the previous wording was confusing, because "extract" can mean "to remove from", as in getting the brains out of the heads. I made these edits:, , in which I linked the word to Extraction (chemistry), which was indeed what Hughes was doing (in other words, separating molecules that were soluble in acetone from solid material that was left behind – that solution or "extract" was the so-called "soup").
 * Page numbers: Sources 5 and 6 already have page numbers specified: 4 and 213, respectively. The only other book source is number 3, which does not show any page numbers at all (at least in the online version, and I do not now have a hard copy).
 * Source 1: It's used in a way that fully conforms to WP:BLPSELFPUB, because it is used only to source his career history (essentially his CV). It's pretty common to use university profile pages for simple biographical facts in biographies written under WP:PROF.
 * Enkephalins: Per our pages on enkephalin, met-enkephalin, and leu-enkephalin, met- and leu- are the only two. Here is Hughes' actual paper (now added to the page), listing those two:.
 * --Tryptofish (talk) 21:34, 15 January 2017 (UTC)
 * Symbol confirmed.svg Good to go - everything has been addressed; please ensure to follow up your QPQ. (BTW: I don't know how I missed that 'extraction' could be extraction (chemistry) instead of physical extraction. Or the ref page numbers, for that matter.) Mind  matrix  19:37, 16 January 2017 (UTC)
 * Thanks for your thoughtful review, and will do on the QPQ. --Tryptofish (talk) 23:34, 16 January 2017 (UTC)