Tennessee State Route 261

State Route 261 (SR 261) is a north–south secondary state highway that is located entirely in Macon County in Middle Tennessee. The route’s length is roughly 13.8 mi.

Route description
SR 261's southern terminus is located in Lafayette at a junction with SR 52. SR 261 travels for 0.2 mi to the Public Square in downtown Lafayette to run concurrent with SR 10 for an additional 0.5 mi.

SR 261 travels northeastward while being known as Galen Road, traversing the unincorporated community of Galen. Its northern terminus is the point where it becomes Kentucky Route 382 (KY 382) at the Kentucky state line in southern Monroe County near Bugtussle.

History
Until 2023, the road beyond SR 261's eastern terminus at the state line was signed as a split section of KY 87, which was separated into two segments on the Kentucky side of the state line. That segment was re-signed as KY 382 in April 2023.