Thomas Chamberlayne

Thomas Chamberlayne may refer to:


 * Sir Thomas Chamberlayne (judge) (died 1625), English judge who served as Chief Justice of Chester
 * Sir Thomas Chamberlayne, 1st Baronet (died 1643), of Wickham, Oxfordshire supported the Royalist cause in the English Civil War. He was Sheriff of Oxfordshire in 1643
 * Sir Thomas Chamberlayne, 2nd Baronet (c. 1635–1682), one of few men to receive a renewal of the baronetcy from the Lord Protector Oliver Cromwell
 * Thomas Chamberlayne (cricketer) (1805–1876), English cricketer and yachtsman
 * Thomas Chamberlayne (priest), Dean of Bristol, 1739–1757