Thomas Smythe (disambiguation)

Thomas Smythe (c. 1558 – 1625) was an English merchant and politician.

Thomas Smythe may also refer to:
 * Thomas Smythe (customer) (1522–1591), English collector of customs duties
 * Sir Thomas Smyth, 2nd Baronet (died 1732), British Army officer and politician
 * Thomas Smythe, 1st Viscount Strangford (1599–1635), viscount in the Peerage of England
 * Thomas Smythe (artist), (1825–1906) English artist based in Suffolk