Tuolumne

Tuolumne may refer to:


 * Tuolumne River, one of the major rivers draining the western slope of the Sierra Nevada mountains
 * Tuolumne Grove, of giant sequoia trees, in Yosemite National Park
 * Tuolumne Meadows, in the eastern section of Yosemite National Park
 * Grand Canyon of the Tuolumne, also in Yosemite National Park
 * Tuolumne County, California, located in the Sierra Nevada
 * Tuolumne City, California, an unincorporated community in Tuolumne County
 * Tuolumne Peak
 * "Tuolumne", a song by Eddie Vedder from the soundtrack for Into the Wild