Twentieth Century Club

Twentieth Century Club may refer to:


 * Twentieth Century Club (Buffalo, New York), listed on the National Register of Historic Places, the first club run by women, for women, in the United States
 * Twentieth Century Club of Lansdowne in Pennsylvania, listed on the National Register of Historic Places
 * 20th Century Club (Reno, Nevada) listed on the National Register of Historic Places in Washoe County, Nevada
 * Twentieth Century Club (Pittsburgh) at the University of Pittsburgh, a contributing property to the Schenley Farms National Historic District