U16

U16 may refer to:

Naval vessels

 * GERMAN SUBMARINE U-16, various vessels
 * HMS Amethyst (U16), a Black Swan-class sloop of the Royal Navy
 * HMS Grimsby (U16), a Grimsby-class sloop of the Royal Navy
 * SM U-16, a submarine of the Austro-Hungarian Navy

Other uses

 * Bugatti U-16, an automobile engine
 * Cubitruncated cuboctahedron
 * Small nucleolar RNA SNORD16
 * Uint16_t, an 16-bit unsigned integer
 * Uppland Runic Inscription 16
 * U16, or under-16, a type of basketball tournament by FIBA