U22

U22 may refer to:

Naval vessels

 * GERMAN SUBMARINE U-22, various vessels
 * HMS Folkestone (U22), a sloop of the Royal Navy
 * SMU U-22 (Austria-Hungary), a submarine of the Austro-Hungarian Navy

Other uses

 * U22 (album), by Irish rock band U2
 * Beretta U22 Neos, a pistol
 * Beechcraft QU-22 Pave Eagle, an American utility aircraft
 * Small nucleolar RNA SNORD22
 * Uppland Runic Inscription 22