U5

U5 or U-5 may refer to:

Biochemistry

 * U5 spliceosomal RNA
 * mtDNA haplogroup U5, within Haplogroup U

Aviation

 * SkyUp MT (IATA code U5), a Maltese airline subsidiary of SkyUp Airlines
 * Karinou Airlines (former IATA code: U5), former airline of the Central African Republic
 * USA3000 Airlines (former IATA code: U5), former airline based in Pennsylvania, US

Land transport

 * U5 (Berlin U-Bahn), a subway line in Germany
 * U-5, a Munich U-Bahn subway line in Germany
 * Aiways U5, a 2019 Chinese electric car model
 * Luxgen U5, a 2017 Taiwanese car model
 * Utah State Route 5 (disambiguation), one of two American highways
 * Beijing U5, a Chinese car

Submarines

 * German submarine U-5, several submarines
 * SM U-5 (Germany), the lead boat of the class
 * U-5-class submarine (Austria-Hungary), a class of three built 1908–1911
 * SM U-5 (Austria-Hungary), the class's lead boat

Other uses

 * U5, a music partnership between the X5 Music Group and Universal labels
 * U5, an unemployment figure released by the United States Bureau of Labor Statistics
 * Ultima V: Warriors of Destiny, a 1988 computer role-playing game