U50

U50 may refer to:

Naval vessels

 * GERMAN SUBMARINE U-50, various vessels
 * HMS Rochester (U50), a sloop of the Royal Navy
 * U-50-class submarine of the Austro-Hungarian Navy

Other uses

 * GE U50, a diesel-electric locomotive
 * Small dodecicosahedron
 * Small nucleolar RNA SNORD50
 * U50 statistic, in computational biology
 * Uppland Runic Inscription 50