Uronate dehydrogenase

In enzymology, an uronate dehydrogenase is an enzyme that catalyzes the chemical reaction


 * D-galacturonate + NAD+ + H2O $$\rightleftharpoons$$ + NADH + H+

The 3 substrates of this enzyme are D-galacturonate, NAD+, and H2O, whereas its 3 products are (the lactone of D-galactarate), NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is uronate:NAD+ 1-oxidoreductase. Other names in common use include uronate: NAD-oxidoreductase, and uronic acid dehydrogenase.