User:99kiru12/sandbox

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Practice Editing Here (Nov 15th in-class Wiki session work)

 * This is a place to practice clicking the "edit" button and practice adding references (via the citation button).

Task:


 * 1) Find a peer-reviewed journal article on PubMed. Practice inserting your citation in the above space using the "cite" tool
 * 2) Choose one "B-level" medical article on Wikipedia from the following list: https://wp1.openzim.org/#/project/Medicine/articles?quality=B-Class&importance=High-Class
 * 3) Practice editing live on Wikipedia by finding a typo in the text or improving the clarity/readability of a sentence by adjusting a few words in a sentence.

Assignment # 3- please post an anonymous copy here!
Proposed change: The addition of the following sentence: “Molecular studies of skin biopsies, including immunohistochemistry and polymerase chain reaction techniques, may be undertaken to supplement clinical and histopathological findings and diagnose MF.”

Location of change: Following the section on Pautrier’s microabcesses.

Controversy regarding proposed change: Not applicable. The use of molecular studies are well-cited in the literature and in clinical practice guidelines.

Rationale for proposed change: The Wikipedia page currently outlines key histopathological findings from skin biopsies including Pautrier’s microabcesses, epidermotropics and T-cells with cerebriform nuclei. The page does not, however, provide details regarding ancillary tests that may be needed to confirm diagnosis of Mycosis fungoides. Immunohistological studies and polymerase chain reaction techniques are well-cited in the literature and international and national clinical practice guidelines. These techniques assist in the analysis of T-cell antigen receptor expression and arrangement. Thus, this modification to the Wikipedia page aims to fill the gaps regarding supplemental molecular studies undertaken in the diagnosis of MF and provides additional details regarding skin biopsy assessments.

Citation: Hristov, Alexandra C et al. “Cutaneous T‐cell lymphomas: 2021 update on diagnosis, risk‐stratification, and management.” American Journal of Hematology 96 (2021): 1313 - 1328.  https://doi.org/10.1002/ajh.26299 

Critique of Source: The citation selected is a review of updates on the diagnosis, prognosis, and treatment of Mycosis fungoides published in the American Journal of Hematology. As a secondary source, the information provided in the article is consolidated by multiple primary sources, therefore reducing the possibility of bias. Further, the authors of this review are well-established in the fields of pathology and dermatology. This research team has also published similar updates on Mycosis fungoides and other cutaneous T-cell lymphomas in previous yearly updates. Additionally, this review was published in June 2021 and therefore, there is reduced chance for dated information on diagnosis. Authors disclosed that there were no conflicts to declare and therefore there was no overt bias in this article.

What to post on the Wikipedia article talk page (part of assignment 3)

 * This will also be covered on Nov 15th in class. Your group should use the below template to share an outline of your proposed improvements (including your new wording and citations). Article talk pages are not places to share your assignment answers. The Wikipedia community will be more interested in viewing your exact article improvement suggestions including where you plan to improve the article (which section), what wording you suggest, and the exact citation (Note: all citations must meet WP:MEDRS)
 * You will not be able to paste citations directly from your sandbox to talk pages (unless you are interested in editing/learning Wiki-code in the "source editing" mode). We suggest re-adding your citations on the talk page manually (using the cite button and populating the citation by pasting in the DOI, website, or PMID). You will have to repeat this process yet again when you edit the actual article live.
 * Talk Page Template: CARL Medical Editing Initiative/Fall 2021/Talk Page Template