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Introduction For one reason or another, many variables cannot be manipulated directly. One deterrent to the manipulation of variables in experiments is the ethical considerations, which all scientists must have. It is ethical to survey or otherwise observe the use of drugs by college students as long as permission is obtained. By no stretch of the imagination, however, would it be ethical to create a group of drug abusers and compare their activities with a non abusers’ group that we have also created.