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Niccolò Lorini was born in Florence in 1544 and at a very young age entered the Dominican Order. He first entered the convent of Santa Maria Novella, then in 1580 was nominated prior of San Domenico in Fiesole, and in 1582 was transferred to San Gimignano. He earned the rank of Preacher General of the Order and was appointed lecturer in ecclesiastical history at the University of Florence. In early November 1612 Lorini declared in a dispute that the doctrine of Copernicus violated Holy Scripture. Lorini's position had no immediate consequences, but two years later, in 1614, following the attack against Galileo by his fellow friar Tommaso Caccini (1574-1648), he sent Cardinal Paolo Camilla Sfrondati of the Congregation of the Index a copy of the Letter to Benedetto Castelli. These machinations against Galileo also had the backing of the Archbishop of Florence, Alessandro Marzimedici. We have no news of Lorini after 1617.

Shortly after Galileo's arrival in Florence, Caccini fell in with the so-called "Pigeon League," named after Lodovico delle Colombe,[1] an arch-enemy of Galileo. The group included his fellow Dominican Niccolò Lorini and the Archbishop of Florence. Lorini was the first to attack Galileo from the pulpit, toward the end of 1612, but in the face of an uproar among the friends of Galileo quickly wrote a letter of apology. Lorini forwarded a mangled copy of Galileo's letter to Castelli to Rome, and Galileo then sent the correct original version to Rome as well.

In late 1614 or early 1615, one of Caccini's fellow Dominicans, Niccolò Lorini, acquired a copy of Galileo's letter to Castelli. Lorini and other Dominicans at the Convent of San Marco considered the letter of doubtful orthodoxy, in part because it may have violated the decrees of the Council of Trent

Niccolò Lorini was born in Florence in 1544. He served as a Preacher General Dominican Order and a lecturer in ecclesiastical history at the University of Florence. He is most famous for his involvement in the Galileo affair. Lorini instigated the events of 1616 by sending Rome a copy of Galileo's to Benedetto Castelli.