User:AgMD1/sandbox

This long-lasting depolarization in individual neurons, due to an influx of Ca2+ from outside of the cell. This leads to extended opening of Na+ channels and repetitive action potentials. The following hyperpolarization is facilitated by γ-aminobutyric acid (GABA) receptors or potassium (K+) channels, depending on the type of cell.

There are proposed mechanisms of the spread and recruitment of neurons, including an increase in K+ from outside the cell, and increase of Ca2+ in the presynaptic terminals. These mechanisms blunt hyperpolarization and depolarizes nearby neurons, as well as increasing neurotransmitter release.

References:

1)   Lowenstein DH. Seizures and Epilepsy. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. (2018) Harrison's Principles of Internal Medicine, 20e New York, NY: McGraw-Hill.

comments
Good start here! If these are your proposed changes, please expand to explain what "this" means in the first sentence. Please also add your refs using the PMID/DOI tool and format everything just like you were editing live on Wikipedia. There are also a lot of technical terms that could use wikilinks. If you are not done here, please disregard this comment!JenOttawa (talk) 03:32, 6 November 2018 (UTC)