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The first-ever empirically-based Physical Activity Guidelines for Americans were published by the United States Department of Health and Human Services (HHS) in 2008. These guidelines provided physical activity recommendations for people aged six years and older, including those with many chronic health conditions and disabilities. The science-based Guidelines recommend a total amount of physical activity per week to achieve a range of health benefits. In 2018, HHS released an update to the first set of guidelines. This 2018 edition provides guidelines for people aged three years and older and summarizes the new knowledge gained from studies that were conducted since the first edition was released in 2008.

These Guidelines can be tailored to meet individual interests, lifestyles, and goals. Recommendations in the Guidelines can be incorporated within daily routines and allow activities—like walking, biking, or dancing—to be integrated.

The main message is that regular physical activity over months and years can produce long-term health benefits and reduce the risk of many diseases. The second edition includes new evidence that shows physical activity also has many immediate health benefits such as reduced anxiety and blood pressure. The messages from the Physical Activity Guidelines are also found in the Dietary Guidelines for Americans which provide recommendations for healthy food choices and regular physical activity.

Health professionals and policymakers are the primary audiences for the Physical Activity Guidelines for Americans. However, the information is useful for anyone interested in improving the health of his/her community members and other individuals. HHS also produced a consumer friendly communications campaign, Move Your Way, which provides tools and resources for the public to help them meet the Guidelines.