User:Akanazunwa/Ovine rinderpest

Microscopic lesions
Microscopic study of both natural and experimental cases revealed congestion and edema of the lungs, while in other cases it revealed a network of fibrin infiltrated with neutrophils, the formation of syncytia and gaint cells, and the presence of a pink-colored bacterial colony. There was infiltration of neutrophils and mononuclear cells within the alveoli, bronchioles, alveolar wall, and interstitium of the lung. Microscopic analysis also revealed that there was interstitial pneumonia followed by sloughing of the bronchial epithelium in the lungs and the prominence of type II pneumocytes. Numerous inflammatory cells were found in the submucosa and lamina propria of intestinal samples, and vacuolar degeneration and syncytial cells, which are microscopic features, were observed in hepatocytes of liver samples from goats. Periportal multifocal lymphocytic infiltrations were common in the liver parenchyma.

Leptomeningitis and nonsuppurative encephalitis were visible in brain sections under a microscope, and these conditions were characterized by vascular congestion, hemorrhages in the parenchyma, perivascular cuffing with mild to moderate mononuclear cells (mostly lymphocytes and few macrophages), focal to diffuse microgliosis, neuronal degeneration, satellitosis, and neuronophagia.

In summary Epithelial cells, alveolar macrophages, lungs, and hepatocytes all showed histopathological alterations, primarily infiltrations of inflammatory cells, syncytia, and presence of intranuclear and/or intracytoplasmic eosinophillic inclusions.