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= Illicium anisatum =

Illicium anisatum, with common names Japanese star anise, aniseed tree, and sacred anise tree, known in Japan as Shikimi (樒), is a tree closely related to the Chinese star anise (Illicium verum). Since it is highly toxic, the fruit is not edible; instead, the dried and powdered leaves are burned as incense in Japan. Its branches and evergreen leaves are considered sacred by Japanese Buddhists due to their ability to remain fresh after pruning.

Illicium anisatum is native to Japan. It is similar to the Chinese star anise, but its fruit is smaller and with a weaker odour, which is said to be more akin to cardamom than to anise. Due to its poisonous nature, its seeds have been used as a fish poison as well as a natural agricultural pesticide to repel animals from digging the ground. Its seeds have also been used medicinally to treat toothache and dermatitis topically, since it is unsuitable for internal use.

Toxicity and accidental use in food products
Japanese star anise contains anisatin, shikimin, and sikimitoxin, which cause severe inflammation of the kidneys, urinary tract, and digestive organs. Other compounds present in toxic species of Illicium are safrole and eugenol, which are not present in the edible Chinese start anise and are used to identify its toxicity. Shikimic acid, a substance also present in Japanese star anise, is so-called after the plant's Japanese name.

In Europe, Chinese star anise tea is often used as a stress-relief tea. Cases of illness have been reported in France, Spain, and Switzerland after people were reported consuming contaminated Chinese star anise tea with Japanese star anise. This contamination hospitalized many people with epilepsy, hallucinations, and nausea all as a result of the toxin anisatin, found in the Japanese star anise. In 2001, there was a large outbreak of toxicity in the Netherlands due to accidental contamination of a tea blend containing more than 6 different tea plants with the Japanese star anise.

Due to its morphological similarities, it is impossible to distinguish Chinese and Japanese star anise in its dried or processed form by its appearance only, and can only be unequivocally determined by using botanical microscopy. This process must be done before the plants have been made into tea and dried out.

Cases of product recalls have been reported when products containing star anise were found to be contaminated by Japanese anise. Cases of consumers admitted to hospital with neurological symptoms after ingesting excessive doses of star anise or smaller doses of products contaminated with Japanese anise have also occurred.

Essential oil components
The essential oil of air-dried I. anisatum seeds obtained by hydrodistillation was analysed by GC–MS. Fifty-two components were identified in the essential oil, the main component being eucalyptol (21.8%).