User:Alexandre.maire/sandbox

The miR-19 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. Within the human and mouse genome there are three copies of this microRNA that are processed from multiple predicted precursor hairpins:


 * mouse (MI0000546, MI0000688, MI0000718)
 * human (MI0000073, MI0000074, and MI000075).

miR-19 has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000011). In this case the mature sequence is excised from the 3' arm of the hairpin precursor.

Targets of miR-19
It has been shown that the 3' UTR of the ATXN1 gene contains 3 target sites for miR-19, and that this microRNA shows moderate down regulation of reporter genes containing the ATXN1 3' UTR. ATXN1 is also regulated by miR-101, and miR-130.