User:Amy.argabright/Choose an Article

Article Selection
Please list articles that you're considering for your Wikipedia assignment below. Begin to critique these articles and find relevant sources.

Option 1

 * Article title Cleavage and polyadenylation specificity factor
 * Article Evaluation
 * Issues
 * Vague content with most of the introduction information going over what the poly(A) signal sequence is
 * Intro says it's the first protein to bind but in structure it is listed as a protein complex
 * Only two citations Improvements
 * Crystal structure could be added
 * In depth explanation of specificity for poly(A) signal


 * Sources
 * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855568/?tool=pmcentrez&report=abstract
 * https://onlinelibrary-wiley-com.aurarialibrary.idm.oclc.org/doi/full/10.1002/prot.22748

Option 2

 * Article title
 * Viscotoxins


 * Article Evaluation
 * This is a stub with the bare minimum explanation. There are interesting articles about the proteomic evaluation of bioactive compounds for mistletoe including viscotoxins. They also have potential as antimicrobial agents.


 * Sources
 * https://www.mendeley.com/catalogue/68b44ca5-ffbf-3039-8bd4-2c38823404a6/
 * https://link-springer-com.aurarialibrary.idm.oclc.org/article/10.1007%2Fs12010-016-2257-7

Option 3

 * Article title
 * Hydrogenase (NAD+, ferredoxin) OR Ferredoxin hydrogenase OR Nickel-dependent hydrogenase


 * Article Evaluation
 * All articles are stubs- the 2nd more complete than the 1st and 3rd. The 2nd could still use some fleshing out including types and details of organisms it's found in. This would be interesting to do because it is one of the only enzymes known for acetogenesis (CO2 -> H2) in gram positive bacteria. The first source talks about two model organisms with this enzymatic activity.


 * Sources
 * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591994/?tool=pmcentrez&report=abstract
 * https://www.mendeley.com/catalogue/92fccabb-cf21-3375-a5fb-8cbe9570f29d/

Option 4

 * Article title
 * Enkephalin


 * Article Evaluation
 * Stub is highly technical. Information could be simplified. Needs more sources. Found a cool paper about it's use in nanotechnology. It's definitely a lesser known endorphin.


 * Sources
 * https://www.proquest.com/docview/1753560764?pq-origsite=summon&accountid=14506 https://pubs-acs-org.aurarialibrary.idm.oclc.org/doi/10.1021/acs.biomac.6b00725

Option 5

 * Article title
 * Butyrylcholinesterase


 * Article Evaluation
 * Could use more details to distinguish between acetylcholinesterase. Only has a link to inhibited by map but no description of allosteric interactions. Pretty cool that it can be a prophylatic to nerve gas agents and cocaine addiction. Its inhibition is a target of interest in Alzheimer's.


 * Sources
 * https://www-sciencedirect-com.aurarialibrary.idm.oclc.org/science/article/pii/S0300483X0600713X https://www.proquest.com/docview/1540859866?pq-origsite=summon&accountid=14506