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Epidemiology
Uterine cancer has a high incidence worldwide, with approximately 3.1% of women diagnosed during their lifetime. Uterine cancer resulted in 45,000 deaths worldwide in 1990, with this number increasing to 58,000 deaths in 2010. The incidence of uterine cancer varies in different regions of the world. North America and Northern Europe have the highest incidence of uterine cancer. Asia, Southern Europe, Australia and South America have moderate incidence rates, with the lowest existing rates in Africa and Eastern Asia. Although the incidence rate is high, the survival rates are also high with 81.2% of women with uterine cancer surviving for five years. This rate is higher with more localized cancer at 95% survival rate for five years and lower for a distant spread of the cancer, at a 16.8% survival rate for five years.

Ethnicity

The rates of incidence and death for uterine cancer differ depending on race. The incidence is highest for white women, with 28.1 new cases per 100,000 persons. Black women had a similar incidence with 27.4 new cases per 100,000 persons. Other ethnic groups had lower incidences, Hispanic women had 24.1 new cases per 100,000 persons, Asian/Pacific Islander women had 20.8 new cases per 100,000 persons, and American Indian/Alaska Native women had 19.7 new cases per 100,000 persons. For the death rates of uterine cancer, black women had the highest rates, 8.5 deaths per 100,000 persons. The death rates for the other ethnic groups were dramatically lower. White women had 4.4 deaths per 100,000 persons, Hispanic women had 3.9 deaths per 100,000 persons, American Indian/Alaska Native women had 3.5 deaths per 100,000 persons, and Asian/Pacific Islander women had 3.1 deaths per 100,000 persons.

United Kingdom

Uterine cancer is the fourth most common cancer in women in the UK (around 8,500 women were diagnosed with the disease in 2011), and it is the tenth most common cause of cancer death in women (around 2,000 people died in 2012).

United States

In the United States, uterine cancer is the most commonly diagnosed invasive cancer of the female reproductive system. The number of women diagnosed with uterine cancer has been steadily increasing, with 35,040 women diagnosed in 1999 and 56,808 diagnosed in 2016. The age-adjusted rate of new cases in 1999 was 23.9 per 100,000 and has increased to 27.3 per 100,000 in 2016. The incidence of uterine cancer increased even more in 2019, with an approximated 61,880 new cases.

Uterine cancer has a high prevalence in the United States, with approximately 772,247 women with the disease in 2016.