User:Andrew Su/ITK (gene)

IL2-inducible T-cell kinase, also known as ITK, is a which in humans is encoded by the ITK  gene.

Function
This gene encodes an intracellular expressed in s.  The protein is thought to play a role in T-cell proliferation and differentiation.

Structure
This protein contains the following domains, which are often found in intracellular kinases:


 * N-terminus – (pleckstrin homology domain)
 * BTK – Bruton's tyrosine kinase Cys-rich motif
 * – (Src homology 3)
 * – (Src homology 2)
 * C-terminus – tyrosine kinase, catalytic domain

Protein interactions
The protein encoded by this gene has been found to interact with, , , , , , , , and in multiple protein interaction studies.