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Many drugs cause skin irritation when combined with UV light exposure (photosensitization), however, some of these medications also have carcinogenic effects when combined with UV exposure.[1]

One drug that is well-known to be photocarcinogenic is psoralen [molecule image]. Psoralen is used in conjunction with UV light exposure to treat various inflammatory skin conditions, but the incidence of skin cancer in patients treated with it over a long term has been shown to increase over that of untreated patients.[2] The use of tetracycline antibiotics combined with UV exposure has also been shown to increase the risk of skin cancer.[3]

http://cebp.aacrjournals.org/content/19/11/2942 https://onlinelibrary.wiley.com/doi/pdf/10.1111/phpp.12085 https://www.nature.com/articles/bjc2017378