User:Apelk003/Bile acid

Secondary bile acids[edit]
Once secreted into the lumen of the intestine, bile salts are modified by gut bacteria. They are partially dehydroxylated. Their glycine and taurine groups are removed to give the secondary bile acids, deoxycholic acid and lithocholic acid. Cholic acid is converted into deoxycholic acid and chenodeoxycholic acid into lithocholic acid. All four of these bile acids are recycled, in a process known as enterohepatic circulation.

- something to add is about each secondary bile acid. For example adding that Deoxycholic acid is absorbed in the colon where it can then enter the entereohepatic circulation where it then is conjugated in the liver and secreted within the bile. For Lithocholic acid it can be fairly insoluble and a very small percentage is reabsorbed.

- I found that the circulating BA pool is composed of about 20-30% of deoxycholic acid while only about 5% is of lithocholic acid.