User:Astghulia/sandbox

Virome refers to the collection of nucleic acids, both RNA and DNA, that make up the viral community associated with a particular ecosystem or holobiont. The word is derived from virus and genome and first used by Forest Rohwer and colleagues to describe viral shotgun metagenomes.[1] All macro-organisms have viromes that include bacteriophage and viruses. Viromes are important in the nutrient and energy cycling,[2] development of immunity,[3] and a major source of genes through lysogenic conversion.[4]

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Virome refers to the collection of nucleic acids, both RNA and DNA, that make up the viral community associated with a particular ecosystem or holobiont. The word is derived from virus and genome and first used by Forest Rohwer and colleagues to describe viral shotgun metagenomes.[1] All macro-organisms have viromes that include bacteriophage and viruses. Viromes are important in the nutrient and energy cycling,[2] development of immunity,[3] and a major source of genes through lysogenic conversion.[4] eli astth] [|sandbox] Contents 1	History 2	Methods of study 3	Virus hosts 4	References History[edit source] Viromes were the first examples of shotgun community sequence,[5] which is now known as metagenomics. In the 2000s, the Rohwer lab sequenced viromes from seawater,[5][6] marine sediments,[7] adult human stool,[8] infant human stool,[9] soil,[10] and blood.[11] This group also performed the first RNA virome with collaborators from the Genomic Institute of Singapore.[12] From these early works, it was concluded that most of the genomic diversity is contained in the global virome and that most of this diversity remains uncharacterized.[13] This view was supported by individual genomic sequencing project, particularly the mycobacterium phage.Astghulia (talk) 09:30, 7 November 2018 (UTC)astghulia