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This is a page under development that may replace Annals of Internal Medicine

Annals of Internal Medicine (Ann Intern Med; ISSN 0003-4819) is an academic medical journal published by the American College of Physicians (ACP). It publishes research articles and reviews in the area of internal medicine.

An archive of issues from 1993 is available at www.annals.org in text and PDF (from 1999) formats. Material over six months old is freely accessible, and access to all papers is also provided free of charge to developing countries.

Annals of Internal Medicine had a 2005 impact factor of 13.254, which makes it among the most-cited of general clinical medical journals, only exceeded by JAMA, Lancet and New England Journal of Medicine. In 2005, Annals circulation approximated 90,000.

History
Founded in 1927, Annals of Internal Medicine has been published twice monthly since 1988. Its current editor is Harold C. Sox. See Huth 1977 and Huth 2002  for details of the journal's history.

Impactful Articles
The following are the 10 most cited articles published at the Annals as of 2006:

1. 	 Grady D, Rubin SM, Petitti DB, et al. Hormone-Therapy To Prevent Disease and Prolong Life In Postmenopausal Women. Annals of Internal Medicine 117 (12): 1016-1037 Dec 15 1992. Times Cited: 1475 2. 	Fukuda K, Straus SE, Hickie I, et al. The Chronic Fatigue Syndrome - A Comprehensive Approach To Its Definition and Study. Annals of Internal Medicine 121 (12): 953-959 Dec 15 1994. Times Cited: 1108 3. 	Koren MJ, Devereux RB, Casale PN, et al. Relation of Left-Ventricular Mass and Geometry To Morbidity and Mortality In Uncomplicated Essential-Hypertension. Annals of Internal Medicine 114 (5): 345-352 Mar 1 1991. Times Cited: 1070 4. 	Hoffman GS, Kerr GS, Leavitt RY, et al. Wegener Granulomatosis - An Analysis of 158 Patients. Annals of Internal Medicine 116 (6): 488-498 Mar 15 1992. Times Cited: 1007 5. 	Levey AS, Bosch JP, Lewis JB, et al. A More Accurate Method To Estimate Glomerular Filtration Rate From Serum Creatinine: A New Prediction Equation. Annals of Internal Medicine 130 (6): 461+ Mar 16 1999. Times Cited: 970 6. 	Love PE, Santoro SA. Antiphospholipid Antibodies - Anticardiolipin and the Lupus Anticoagulant In Systemic Lupus-Erythematosus (SLE) and In Non-SLE Disorders - Prevalence and Clinical-Significance. Annals of Internal Medicine 112 (9): 682-698 May 1 1990. Times Cited: 961 7. 	Bone RC The Pathogenesis of Sepsis. Annals of Internal Medicine 115 (6): 457-469 Sep 15 1991. Times Cited: 951 8. 	Guyatt GH, Feeny DH, Patrick DL. Measuring Health-Related Quality-Of-Life. Annals of Internal Medicine 118 (8): 622-629 Apr 15 1993. Times Cited: 942 9. 	McGuire WP, Rowinsky EK, Rosenshein NB, et al. Taxol - A Unique Antineoplastic Agent With Significant Activity In Advanced Ovarian Epithelial Neoplasms. Annals of Internal Medicine 111 (4): 273-279 Aug 15 1989. Times Cited: 875 10. 	Graham DY, Lew GM, Klein PD, et al. Effect of Treatment of Helicobacter-Pylori Infection on the Long-Term Recurrence of Gastric or Duodenal-Ulcer - A Randomized, Controlled-Study. Annals of Internal Medicine 116 (9): 705-708 May 1 1992. Times Cited: 810

Innovations in Medical Publishing

 * 1) 1987: The proposal for structured abstracts is published in the April issue; first structured abstracts are published.
 * 2) 1994: Research on the effects of peer review
 * 3) 1997: Guidelines for the use of Bayesian interpretation of significance testing included in information for authors
 * 4) 1999: Summaries for patients introduced for original research articles
 * 5) 2003: Editors' notes introduced to summarize the articles' findings, implications, and limitations
 * 6) 2004: Limitations section added to standard structured abstracts