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Penicillin is a widely used medication that is effective for the treatment of a wide variety of bacterial infections in adults and children. Some side effects are expected, some are common but serious, some are uncommon and not serious and others are rare but serious.

Adults
Common adverse drug reactions (≥ 1% of people) associated with use of the penicillins include diarrhoea, hypersensitivity, nausea, rash, neurotoxicity, urticaria, and superinfection (including candidiasis). Infrequent adverse effects (0.1–1% of people) include fever, vomiting, erythema, dermatitis, angioedema, seizures (especially in people with epilepsy), and pseudomembranous colitis. [subscription required][outdated?]