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Early Life
Muriel Petioni was born to Charles Augustin Petioni and Rose Alling in 1914 in the country of Trinidad. As a child, her father was exiled to Harlem, and during this time he become a physician. Once, her family was able to join him in Harlem, her father was running a medical office from their home. As a child, Muriel enjoyed answering the door and the phone for her father's patients. This is where her love for medicine grew, and her parents wildly encouraged her to pursue her dreams.

In 1937, Muriel graduated from Howard University College of Medicine, as the sole female in her graduating class. Shortly after obtaining her MD, Muriel had a two year internship at Harlem Hospital, then later became a physician at several universities.