User:Belunny23/GATA transcription factor

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Some research that has been done on the GATA transcription factor for its role in the development of breast cancer suggest that a specific GATA transcription factor GATA3 can actually inhibit further growth of breast cancer cells.

The complete mechanism in which this happens is still not clear. However, research has suggested that the GATA transcription factor creates an unfavorable chemical environment for the breast cancer tumor cells which inhibits the progression of these cells. One way that has been suggested is that the GATA transcription factor lowers the level of adenosine triphosphate (ATP) in the cell. This creates an unfavorable chemical environment for the breast cancer cells because usually they require high levels of ATP to survive. In addition, research has suggested that there is a specific gene called the TRP1 that is expressed in breast cancer cells and the GATA3 transcription factor plays a role in regulating this gene.