User:Benjah-bmm27/degree/3/GCLJ1

=Mechanisms, GCLJ1=
 * Reaction mechanisms
 * Molecularity
 * Order of reaction
 * Elementary reaction
 * Concerted reaction
 * Stepwise reaction
 * Bodenstein approximation

The philosophy behind reaction mechanism determination
See User:Benjah-bmm27/degree/hps.

Isotopic labelling

 * Solvolysis of phenethyl tosylate, Ph-CH2-CH2-OTs, to phenethyl acetate with acetic acid
 * Simple SN2 with EWGs in the para position on the benzene ring (e.g. p-NO2): ρ ≈ −1.5 (no significant accumulation of charge)
 * EDGs allow a symmetrical phenonium ion intermediate to form: ρ ≈ −1.5 (no significant accumulation of charge)
 * So-called assisted SN1
 * Evidence for symmetrical intermediate comes from scrambling of 13C label (C) on the &alpha;-carbon of phenethyl tosylate:
 * Ar-CH2-CH2-OTs → Ar-CH2-CH2-OAc + Ar-CH2-CH2-OTs