User:BertoHContreras/DNA end resection/BattIe5tar Peer Review

General info

 * Whose work are you reviewing?

(BertoHContreras)


 * Link to draft you're reviewing
 * https://en.wikipedia.org/wiki/User:BertoHContreras/DNA_end_resection?veaction=edit&preload=Template%3ADashboard.wikiedu.org_draft_template


 * Link to the current version of the article (if it exists)
 * DNA end resection

Evaluate the drafted changes
(Compose a detailed peer review here, considering each of the key aspects listed above if it is relevant. Consider the guiding questions, and check out the examples of what feedback looks like.)

Lead
This section provides a pretty good overview of the topic. I would add an explanation on how the DNA is cut, like what enzymes are involved, etc. A figure would also be nice to help visualize the topic.

Background
The background section is written pretty well, but I think it focuses too much on the double strand breaks ( and I would also add an indicator that double strand breaks are later shown as DSBs). I think adding a section on the history of the topic would be helpful, such as who discovered this topic and what experimental methods were used to observe it.

Mechanism
The explanation of the mechanism is pretty good, but it can get a bit confusing to understand with all the different terms everywhere. Maybe separating the first paragraph into three sections for DSBs, NHEG, and HR would be more digestible. In the other two paragraphs, I would add a couple of supporting sentences to help explain the scientific-heavy parts.

Resection of Telomere DSBs
This section is really good, I don't see anything I would change here.

Resection of Mitotic DSBs
This section is pretty scientific jargon-heavy, so I would try to find a way to make it more digestible to people if possible. Otherwise, the explanations are really thorough and provide a lot of thought into how Mitotic DSBs resection works.

Positive and Negative Regulators of DNA Resection
I think this section has the same issue as the previous one as being a bit too jargon heavy. I would try and see it cutting some of the protein names and such would help making it more understandable and concise.