User:Bfpage/sandbox/penile intraepithelial neoplasia

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Penile intraepithelial neoplasia has histological similarities to cervical intraepithelial neoplasia. It is referred to as being pre-cancerous.

Treatment
PIN does not have a standardized method for treatment or diagnosis or management. The natural history of this lesion is unknown. The prevalence of PIN may be greater than invasive cancer of the penis. Studies have not been consistent due to misclassification of PIN histological confirmation and diagnosis based upon biopsied tissue. Prevalence of HPV in PIN varies from 60–100%. Other risk factors for have been identified.