User:Biobelle5/sandbox

Article Evaluation-- Cytochrome c
The primary structure of cytochrome c is said to consist of 100 amino acids but this information was not cited. In addition, the article very briefly mentioned cytochrome c's role in the electron transport chain, but more information regarding the role of cytochrome c as a mobile electron carrier in the electron transport chain would help to enhance the article. As far as the citations, the links did work and supported the claims made in the article. The Talk Page of the article mentioned adding a reference for the molecular weight of cytochrome c (12,000 Da) as well as adding a section on the use of cytochrome c in evolutionary and taxonomic analysis. Overall, this article is neutral and relatively unbiased.

Being bold is important on Wikipedia. Being bold is important on Wikipedia.

Jane Wright
I'd like to add more about her educational history as well as her work on chemotherapy.

Sources

"Jane Cooke Wright." Current Biography Yearbook 29 (1968); 443-445.

Notable Black American Women, ed. Jessie Carney Smith. Detroit: Gale Research, 1992

A Passion for Solving the Puzzle of Cancer: Jane Cooke Wright, M.D. 1919-2013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063385/pdf/onc646.pdf

Notable Women in the Life Sciences: A Biographical Dictionary

Girls Research! Amazing Tales of Female Scientists

Trailblazers: 33 Women in Science Who Changed the World

Cancer Chemotherapy: Past, Present, and Future-- Part 1

The Women's book of world records and achievements

Dr. Jane Cooke Wright (1919-2013) was a revolutionary cancer researcher who developed new techniques for administering cancer chemotherapy. She graduated in 1942 from Smith College with a Bachelor of Arts degree. In 1945, she graduated with honors from New York Medical College. After her father's death, she was appointed director of the Cancer Research Foundation at Harlem Hospital. She is credited with the development of a non-surgical method to deliver potent drugs to cancerous tumors located deep within the kidneys and spleen. Dr. Wright helped elevate chemotherapy from a last resort option to a viable treatment option for cancer patients.

Education
Wright attended Smith College in Northampton, Massachusetts on a four year academic scholarship to study art. During her junior year, at her father's request, she changed her major to pre-medicine. After graduating from Smith in 1942, Dr. Wright attended New York Medical College on a four year scholarship. She graduated with an M.D. in 1945. Soon after, she interned at Bellevue Hospital and completed her residency at Harlem Hospital.

Research/Career
In 1949, Wright accepted a position as a clinician at the Harlem Hospital Cancer Research foundation, founded by her father Dr. Louis Wright. The foundation investigated the effects of chemotherapeutic drugs on cancer treatment. For several years, she conducted tests with chemotherapeutic agents such as triethylene melamine, puromycin, and ACTH and she evaluated folic acid antagonists in adults with leukemia. Among these, the most effective against solid tumor cancers were methotrexate and aminopterin. With her father's death in 1952, Wright was appointed director of the Cancer Research foundation. In 1955, she joined the faculty of New York University Medical Center, as director of cancer chemotherapy research and instructor of research surgery in the Department of Surgery. By 1961, she was named adjunct associate professor of research surgery at New York University Medical School and its affiliates Bellevue and University hospitals. Patients here benefited from the clinical application of new drugs that Dr. Wright and her staff analyzed in the laboratory. In 1957, she found that some drugs were successful in research animals but not in humans while others that showed excellent results on tissue extracts from malignant tumor growth did not always inhibit cancer in the patient. As a result, Wright carefully monitored all chemotherapy patients and worked to develop treatment guidelines to provide maximum benefit to patients. In 1964, Wright developed a non-surgical method, using a catheter system, to deliver potent drugs to tumors located deep within the body (kidneys, spleen, etc). She was also the only women among seven physicians who helped to found the American Society of Clinical Oncology (ASCO). In addition, she was appointed by President Lyndon B. Johnson to the President's Commission on heart disease, cancer, and stroke. By 1967, Dr. Wright's role as head of the chemotherapy department and associate dean at New York Medical College made her the highest ranking African American woman in a U.S. medical institution. She retired from the New York Medical College and cancer research in 1987.

Awards
Mademoiselle magazine (1952)

The National Council of Negro Women (1956, 1963)

New York City's Harriet Beecher Stowe Junior High, the women's division of the Albert Einstein College of Medicine (1965)

Links (1965)

Doctor of Medical Sciences degree by the Women's Medical College of Pennsylvania (1965)

Elected to membership in Sigma Xi (1962)

Elected to membership in Alpha Omega Alpha (1966)